4^th Global Summit on Herbals and Traditional Medicine October 03-04, 2018 Osaka, Japan

Biography:

Russell Smart has completed his Fellowship of the Royal New Zealand, College of General Practitioners. He currently works at Middlemore Hospital and has an interest in traditional Maori medicine Rongoā; medicinal use of plants.

Abstract:

Kawawkawa is one of New Zealand’s most distinctive native plants lives up to this common dictum as an herbal pharmacopoeia with a wide range of health benefits. The plant is aromatic and is commonly known as the pepper tree. This presentation will depict the use of kawakawa in traditional and modern herbal medicine. It will explore the biochemical nature of the known pharmacologically active compounds to help explain the wide ranging medicinal uses of this small evergreen shrub-like tree with large heart-shaped leaves.

Biography:

Anirban Sukul has completed his PhD from Visva-Bharati University and Research Associate-ship from same university. He is the Director of Sukul Institute of Homeopathic Research, Kolkata, India. He has published 22 papers in international journals and authored a book published by Kluwer Academic Publishers, Netherlands. He is conferred the Junior Scientist Award, Life Time Achievement Award, Gold Medal Award (UK), Man of Excellence Award, etc. He is in Board of Editors in many reputed international journals published from London, USA. He is also a Member of Research Committee, LMHI, Germany.

Abstract:

Male adult albino mice were administered potentized Nux vomica 30C (Nux). The drug was mixed with distilled water at 0.05 ml/2 ml water and given at 0.05 ml. Control is blank ethanol solution. Ethanolic extract from the seeds of Strychnos nux-vomica was mixed with 90% ethanol 1:100 and sonicated for 30s at 20 KHz and further diluted and sonicated in 30 steps to produce Nux 30C. Six hours after treatment, mice were given 25% ethanol i.p. at 4 g/kg body weight. The duration of sleep time starting from the loss of righting reflex until its restoration was recorded. Sleep time duration with ethanol was recorded in four sessions for same group of mice with an interval of 10 days between sessions. Treatments: Session-1: Control solution, 2: Nux (oral), and 3: Nux (i.p.). Nux (oral) produced shortest sleep time as compared to other treatments which did not differ from each other significantly with respect to sleep time. In another experiment Nux 30C was prepared with distilled water and pure absolute ethanol by the above process of successive dilution and sonication. These two preparations together with Nux 30C, prepared with 90% ethanol, were tested on mice for their effect on alcohol-induced sleep time. Only Nux 30C prepared with 90% ethanol was effective in reducing the sleep time in mice. It is concluded that the solution structure of ethanol/water mixture carries the specificity of the Nux at ultra-high dilution. It is further concluded that the effect is mediated through oral receptors.

Biography:

Nutda Sutthammikorn has completed her Bachelor’s degree from Mahidol University and Master's degree from Faculty of Medicine at Chiang Mai University. Presently she is pursuing PhD from Chiang Mai University and International Research from Juntendo University Graduate School of Medicine.

Abstract:

Wound healing impairment in the diabetic foot ulcers is the most frequently recognized complication in diabetic patients. Therefore, there is a substantially unmet need to develop new interventions that are effective, cheap and with fewer side effect burdens. Gynura procumbens (GP) is commonly found in Southeast Asian countries. The leaves extract of GP are used in folk medicine for treatment of various ailments such as fever, rash, inflammation, kidney disease, migraine, rheumatism, cancer, viral infection, hypertension, hyperglycemic and hyperlipidemia. However, the effect of GP on the healing of diabetic wounds has not been reported. In this study we examined the effects of GP gel treatment on wound healing in streptozotocin-induced diabetic mice and found that GP treatment significantly promoted wound healing faster than solcoseryl jelly, which is usually used as a wound healing drug in diabetic patients. GP also promoted angiogenesis around the wound area, and significantly increased the skin expression of angiogenin, endothelial growth factor, fibroblast growth factor, transforming growth factor ß1 and vascular endothelial growth factor in both normal and diabetic mice. Moreover, GP elevated the expression of various growth factors in human fibroblasts, keratinocytes, endothelial cells and mast cells. Interestingly, GP promoted keratinocyte and fibroblast proliferation and enhanced fibroblast, keratinocyte and mast cell migration. These findings suggest that GP may be used as a wound healing drug in diabetic ulcers.

Biography:

Maryam is pursuing advanced studies at Shanghai University of Traditional Chinese Medicine. She is a licensed psychotherapist. She holds a Doctorate in public administration with emphasis in healthcare administration from University of La Verne. She holds three master’s degrees from National University: Master of Arts in counseling psychology, in human behavior, and in healthcare administration. She was National University’s lead faculty member managing the public administration undergraduate and graduate programs. She was chief executive officer for a San Diego community clinic. Maryam is executive director and founder of the Cancer Coping Center. She has published articles in peer-reviewed journals and was keynote speaker at various international conferences.

Abstract:

Traditional Chinese medicine (“TCM”) is deeply rooted in Chinese culture, tradition and philosophy. Because of the combination of culture, tradition and philosophy, TCM is inherently integrative providing patients’ comfort, acceptance and, most important, compliance with the TCM therapy. Treating the target health concern in concert with the patient’s mental state expands the TCM integrative approach. Psychotherapy affords the healthcare practitioner the means to treat the mental state of the patient. Treating the health concern in combination with the patient’s mental state may offer successful outcomes or, perhaps, increase the likelihood for success. Given the well documented ‘placebo effect,’ one cannot ignore the benefits of addressing the mental state of patients for successful treatment outcomes. The challenge arises in acceptance of the foregoing approach for several reasons and this poster presentation also considers how to implement an approach.

Biography:

Abstract:

Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinisation, inflammation and bacterial colonization of hair follicles on the face, neck and back by Propionibacterium acnes. There is no ideal treatment for acne, although a suitable regimen for reducing lesions can be found for most patients. New research is needed into the therapeutic comparative effectiveness and safety of the many products available. In this case report it was evaluated, acupuncture therapy used in combination with pharmaceutical medication appeared to be more effective than pharmaceutical medication alone in increasing the number of cured patients with acne. However, further studies are needed to confirm this finding. Here a case report of acne treated with acupuncture from Bangladesh is reported and its effectiveness is highlighted.

Biography:

Arman Zargaran has completed his PhD from Shiraz University of Medical Sciences, Iran. He is an Assistant Professor at the Department of Traditional Pharmacy and Vice Dean for International Affairs in School of Persian Medicine, Tehran University of Medical Sciences. He is also the Member of International Academy of the History of Pharmacy and Iranian Academy of Medical Sciences. He has published more than 120 papers in reputed journals and has been serving as an Editorial Board Member and Reviewer of many peer reviewed journals.

Abstract:

Phytotherapy is a source of finding new remedies for migraine. Traditional chamomile oil (chamomile extraction in sesame oil) is a formulation in Persian Medicine (PM) for pain relief in migraine. An oleogel preparation of reformulated traditional chamomile oil was prepared and then standardized based on chamazulene (as a marker in essential oil) and apigenin via Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) methods, respectively. A crossover doubleblind clinical trial was performed with 100 patients. Each patient took two tubes of drug and two tubes of placebo during the study. Visual Analog Scale (VAS) questionnaires were filled in by the patients and scores were given, ranging from 0 to 10 (based on the severity of pain) during 24 hours. Other complications like nausea, vomiting, photophobia and phonophobia were also monitored. There was 4.48±0.01 μl/ml of chamazulene and 0.233 mg/g of apigenin in the preparation (by correcting the amount with extraction ratio). 38 patients in the drug-placebo and 34 patients in the placebo-drug groups (a total number of 72 patients as per protocol) completed the process in the Randomized Controlled Trial (RCT). Adapted results from the questionnaires showed that pain, nausea, vomiting, photophobia and phonophobia significantly (p<0.001) decreased by using chamomile oleo-gel on the patients after 30 minutes. Results supported the efficacy of chamomile oleogel as a pain relief in migraine without aura.

Biography:

Bandar H Aloufi is a Professor at the Department is Biology, University of Hail in Saudi Arabia.

Abstract:

The lipid profile (total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides) is used as part of a cardiac disease risk assessment. In this research, we investigate the efficiency of Fish oil to decrease the levels of total cholesterol and proteins in Wistar rats (n=60) weighing (225-250 g). Fish oil was fed for seven weeks to Wistar rats. Hematological and physiological parameters were examined by automatic analyzer and the results were statistically analyzed by SPSS.12. In comparison to control rats showed highly significant decrease in values of following physiological parameters; triglycerides, total cholesterol, low density lipoprotein cholesterol, total protein, and in contrast, marked increase in the value of high density lipoprotein cholesterol. These findings indicate that diets containing fish oil significantly improved the physiological parameters of rats. We suggest that fish oil as part of food might improve blood parameters and increase high density lipoprotein cholesterol in rats. We further suggest that fish oil supplementation act as antioxidant agents and an excellent adjuvant therapy for rats.

Biography:

Fanfan Zhou has obtained her PhD from Rutgers, the State University of New Jersey, USA in 2008. She is currently a Senior Lecturer in the School of Pharmacy, the University of Sydney, Australia. She has published more than 70 papers in reputed journals since 2003. She is an Editorial Board Member of two international journals and serves as Reviewer to many prestigious journals.

Abstract:

The Retinal Pigmented Epithelium (RPE) is a monolayer of cells located near the choroidal capillaries that mediates human visual cycle and nourishes other retinal cells. It is known that hypoxia-induced oxidative stress to RPE is a vital cause of many neo-vascular retinal diseases such as the Age-related Macular Degeneration and Diabetic Retinopathy. The therapeutic outcome of these diseases is often disappointing; therefore, it is clinically important to protect RPE cells from hypoxia assault. Betulinic Acid (BA) is a penta-cyclic tri-terpenoid with anti-oxidative property, but little is known about its effect on retinal cells. Our study investigated the protective effect of BA and its derivatives against cobalt chloride-induced hypoxia assault in human RPE cells. Human ARPE-19 cells were exposed to BA and its nineteen derivatives (named as H2-H20) that we customized through replacing moieties at C3 and C17 positions. We found that cobalt chloride reduced cell viability, increased ROS production as well as induced apoptosis and necrosis in ARPE-19 cells. Interestingly, the pretreatment of H7 compound effectively protected cells from acute hypoxia assault caused by cobalt chloride. Our immune-blotting results showed that H7 attenuated the cobalt chloride-induced phosphorylation of Akt, Erk and JNK pathways. All findings were further validated in human primary RPE cells. In summary, the BA derivate H7 has protective effect against the acute hypoxic assault in human RPE cells and may be developed into a candidate agent effective in the prevention of prevalent retinal diseases.

Biography:

Jiwu Wei has completed his MD and Postdoctoral studies from Ulm University and Munich University School of Medicine, respectively. He is the Professor of
Nanjing University School of Medicine, China and a Principle Investigator in Cancer Biological Therapy. He has published more than 25 papers in reputed journals.

Abstract:

The NF-κB/IL-6/STAT3 inflammatory axis is highly activated in a variety of inflammation-related cancers and contributes to suppression of antitumor immunity. In this study, we generated a novel herbal formula NHE-06, a water-decocting extract from six natural herbals, Ficus carica, Taraxacum mongolicum, Angelica sinensis, Lonicera japonica, Pseudo-ginseng and Folium ginkgo. We investigated the anti-inflammatory properties of NHE-06 and its antitumor efficacy in hepatocellular carcinoma, a typical inflammation-related cancer. We found that NHE-06 effectively suppressed NF-κB/IL-6/STAT3 signaling and enhanced antitumor immunity both in vitro and in HCC-bearing mice. In a subcutaneous HCC mouse model, we found that NHE-06 possessed both preventive and therapeutic functions. Moreover, rather than the cytotoxic effects, the antitumor efficacy of NHE-06 was indispensable of intact immunity, since the therapeutic effect was only achieved in immune-competent mice whereas failed in immune-compromised mice. Taken together, the novel formula of the anti-inflammatory NHE-06 effectively restores antitumor immune-surveillance and can be applied for prevention and/or treatment of inflammationrelated cancers.

Biography:

Abstract:

The field sampling and documentation was made at Barangay Baganihan, Marilog district Davao city, Philippines. It aims to determine the ethno-botanical practices and their ecological status of the medicinal plants used by Matigsalug tribe. Respondents were randomly selected aging 18 to 60 years old for the interview using validated survey questionnaires. Overall, there were 35 plants identified with 22 families. Family of Poaceae had the highest number of species. Matigsalug tribe mostly used leaves (28.57%), while the method of preparation was decoction (51.43%) and utilization of these medicinal plants was ingestion (57.1%). The study revealed 22 identified species with a fidelity value of 100%. The disease categories with the highest
informed consensus factor were dermatological diseases (0.9 ICF). Based on the field sampling, there was 36 species with 26 families identified. In terms of species diversity index, Shannon-Wiener Diversity Index was used and obtained its value H’=2.736177 which indicates a high species diversity in the area. The study revealed that the Matigsalug tribe was dependent on medicinal plants for their primary health care need. Therefore, there should be an educational program for awareness of the community on how to improve their practices and protection and conservation of the medicinal plants.

Biography:

Abstract:

By looking at the history and developments of science, we find that many basic sciences such as mathematics, astronomy, philosophy, logic, geometry and physics maintain their logical and historical links with their written sources, and scientists in these fields study previous sources and mastering them in the production of science, innovation and technology in those fields. But in the field of medicine, there is a critical and important historical section that cuts medicine out of its 7,000 year history and puts it in a new and completely different direction, opposing its background. The importance of medicine in the life of all living beings, especially human beings, is a sign of salvation and healing. From the beginning of human life, according to the type of advancement, there have been different types of medicine and now, we have reached the current medicine over the time, sometimes due to shortcomings in modern science, with the return to the previous sciences, we attempt to eliminate the problems. Dependence on chemical drugs due to its harmful effects is a major concern among most people in society. For this reason, some people prefer acupuncture, pressure therapy and traditional or herbal remedies to treat their illnesses. Also, the traditional medicine has been accepted by many people through its success in being healthy. In this article, we try to look
at complementary and alternative medicine and compare the collected findings with current medicine.

Biography:

Mohammad Zashim Uddin is a Professor in the Department of Botany, University of Dhaka, Bangladesh. He has been published 66 research articles, books, book parts in different national and international scientific journals. He served as Biodiversity Expert in 22 research projects in Bangladesh. Apart from his research, he was involved with many scientific affiliated bodies. His current research focuses on traditional healthcare knowledge of herbal medicinal plants, taxonomy and conservation of threatened plants and conservation biology of tropical biodiversity.

Abstract:

The research article highlights the medicinal plants for the treatment of diabetes used by the local people of Bangladesh. The data were collected using semi-structure interviews with key informants during the year of 2014 and 2015. In some cases group discussion and informal conversation with local people were also conducted. A total of 41 medicinal plant species were recorded for the treatment of diabetes. These medicinal plant species assigned to 30 families. Among the medicinal plants, 56% are represented by trees, 25% by herbs, 11% by shrubs and 8% by climbers. The most frequently cited medicinal plants by the local people for the treatment of diabetes were Coccinia cordifolia, Momordica indica, Azadirachta indica, Syzygium cumini,
Terminalia arjuna, Aegle marmelos, Andrographis paniculata, Terminalia chebula, Averrhoa bilimbi and Swietenia mahagani. The data analysis was also confirmed the cultural bound medicinal plants of local people for diabetes treatment using fidelity value index. Among the medicinal plants Abelmoschus esculentus, Carissa carandas, Catharanthus roseus, Citrus aurantiifolia, Citrus grandis, Dillenia indica, Gynura nepalensis, Momordica indica, Swietenia mahagani, Syzygium cumini, Tinospora crispa and Ficus racemosa were attained 100% fidelity level values. Medicinal plants which were most cited by local people for diabetes treatment and medicinal plants with 100% Fl values may further subjected for phytochemical investigation to find pure bioactive compounds for the management of diabetes. As wild medicinal plants are in vulnerable in natural habitats, appropriate policy should be applied for sustainable local resource conservation, economic growth, primary healthcare and community development.