Hawa ZE Jaafar
Director UCTC Universiti Putra Malaysia, Malaysia
Title: Involvement of elicitated Labisia pumila Benth. biofluids in the alleviation of chemotoxicity effect and antitumor activity
Biography
Biography: Hawa ZE Jaafar
Abstract
Phytochemicals derived from plant sources such as phenolics, flavonoids, alkaloids, saponin, tannin and lignin are promoted for the prevention and treatment of many health conditions, including cancer, heart disease, diabetes, and high blood pressure. Recent scientific attention has been directed towards the cancer preventive potential for naturally occurring constituents of antioxidant, vitamins, flavanoids, glucosinolates and organosulfur compounds that have anticarcinogenic or antioxidant potential. Plants products are regarded as potential chemopreventive agents acts to block, reverse or prevent the development of invasive cancers. As plants are generally very responsive to biotic and abiotic factors in altering their physiological, biochemical and morphological properties, exposing herbal plants to elicitors may induce, alter or enhance synthesis of secondary metabolites. Recent work on the use from elicitated local herb biofluids in the alleviation of chemotoxicity effect demonstrated enhanced protective nature of elicitated L. pumila especially on white blood cell and organ weight, and with greater anti-tumor activity in comparison to CPT-11 drugs-treated BDF-1 mice.